T cell receptor BV gene usage in interstitial cellular infiltrates in active Heymann nephritis | Zendy

Huiling Wu | Zendy; Geoff Y. Zhang | Zendy; John Knight | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

T cell receptor BV gene usage in interstitial cellular infiltrates in active Heymann nephritis

Author(s) -

Huiling Wu,

Geoff Y. Zhang,

John Knight

Publication year - 2001

Publication title -

nephrology dialysis transplantation

Language(s) - Uncategorized

Resource type - Journals

SCImago Journal Rank - 1.654

H-Index - 168

eISSN - 1460-2385

pISSN - 0931-0509

DOI - 10.1093/ndt/16.7.1374

Subject(s) - medicine , interstitial nephritis , nephritis , gene , receptor , pathology , immunology , cancer research , genetics , kidney , biology

Infiltration of the kidney by mononuclear cells is a prominent feature of active Heymann nephritis (HN). These cells could be present as a part of generalized inflammatory response, or could be proliferating in response to specific antigens. To examine these questions, we have analysed the T cell receptor (TCR) BV repertoire of T cells infiltrating the renal interstitium at regular time intervals throughout the course of the disease.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research