Open AccessPolymorphism of the cytokine genes in hospitalized patients with Puumala hantavirus infection
Author(s) -
Satu Mäkelä,
Mikko Hurme,
Ilpo AlaHouhala,
Jukka Mustonen,
AnnaMaija Koivisto,
Jukka Partanen,
Olli Vapalahti,
Antti Vaheri,
Amos Pasternack
Publication year - 2001
Publication title -
nephrology dialysis transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.654
H-Index - 168
eISSN - 1460-2385
pISSN - 0931-0509
DOI - 10.1093/ndt/16.7.1368
Subject(s) - puumala virus , medicine , hantavirus , genotype , immunology , odds ratio , hantavirus infection , allele , gene polymorphism , gastroenterology , virus , gene , biology , genetics
Nephropathia epidemica (NE) is a mild type of haemorrhagic fever with renal syndrome caused by Puumala (PUU) hantavirus. The clinical course of NE varies from asymptomatic to fatal. The aim of this study was to establish whether polymorphisms in the cytokine genes are associated with susceptibility to and outcome of NE.
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