Open AccessErythropoietin enhances recovery after cisplatin‐induced acute renal failure in the rat
Author(s) -
Corinne Isnard Bagnis,
Hélène Beaufils,
C. Jacquiaud,
Y. Adabra,
Chantal Jouanneau,
Gilles Le Nahour,
M C Jaudon,
Richard Bourbouze,
Claude Jacobs,
Gilbert Deray
Publication year - 2001
Publication title -
nephrology dialysis transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.654
H-Index - 168
eISSN - 1460-2385
pISSN - 0931-0509
DOI - 10.1093/ndt/16.5.932
Subject(s) - erythropoietin , cisplatin , medicine , renal function , immunostaining , proliferating cell nuclear antigen , kidney , endocrinology , intraperitoneal injection , vascular endothelial growth factor , immunohistochemistry , pathology , urology , chemotherapy , vegf receptors
Erythropoietin (Epo) is a growth factor whose synthesis mainly takes place in the kidney. Epo has been shown to support the growth not only of erythroid progenitor cells but also of certain other cell types. We attempted to establish whether Epo enhances the recovery from acute renal failure induced by cisplatin.
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