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Ultrastructure of basement membranes of peritoneal capillaries in a chronic peritoneal infusion model in the rat
Author(s) -
Machteld M. Zweers,
Laura J. Splint,
Raymond T. Krediet,
Dirk G. Struijk
Publication year - 2001
Publication title -
nephrology dialysis transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.654
H-Index - 168
eISSN - 1460-2385
pISSN - 0931-0509
DOI - 10.1093/ndt/16.3.651
Subject(s) - medicine , peritoneal dialysis , basement membrane , peritoneum , ultrastructure , endocrinology , surgery , urology , pathology
Long-term peritoneal dialysis with glucose- based dialysis solutions has been associated with diabetiform alterations of peritoneal tissue. A peritoneal infusion model in the rat was developed to study the effect of chronic infusion of a glucose-based dialysis solution and an isotonic non-glucose solution on the ultrastructure of the basement membranes of peritoneal capillaries. The effect of ageing was also studied in an untreated control group.

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