Prognostic implications of retinopathy and a high plasma von Willebrand factor concentration in type 2 diabetic subjects with microalbuminuria | Zendy

Agnes Jager | Zendy; Victor W.M. van Hinsbergh | Zendy; Piet J. Kostense | Zendy; J.J. Emeis | Zendy; Giel Nijpels | Zendy; Joost Dekker | Zendy; Robert J. Heine | Zendy; L.M. Bouter | Zendy; Coen D.A. Stehouwer | Zendy

Open Access

Prognostic implications of retinopathy and a high plasma von Willebrand factor concentration in type 2 diabetic subjects with microalbuminuria

Author(s) -

Agnes Jager,

Victor W.M. van Hinsbergh,

Piet J. Kostense,

J.J. Emeis,

Giel Nijpels,

Joost Dekker,

Robert J. Heine,

L.M. Bouter,

Coen D.A. Stehouwer

Publication year - 2001

Publication title -

nephrology dialysis transplantation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.654

H-Index - 168

eISSN - 1460-2385

pISSN - 0931-0509

DOI - 10.1093/ndt/16.3.529

Subject(s) - microalbuminuria , medicine , von willebrand factor , retinopathy , diabetic retinopathy , endothelial dysfunction , diabetes mellitus , type 2 diabetes , type 1 diabetes , albuminuria , endocrinology , kidney disease , platelet

Microalbuminuria in subjects with type 2 diabetes may be heterogeneous with respect to clinical features, renal histology, and prognosis. There may be at least two types of microalbuminuria in diabetes, namely with and without generalized endothelial dysfunction. We investigated whether, among microalbuminuric subjects with type 2 diabetes, the presence of generalized endothelial dysfunction, as indicated by the presence of retinopathy or a high plasma von Willebrand factor (vWf) level, has prognostic implications.

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