Erythropoietin modulates angiotensin II‐ or noradrenaline‐induced Ca2+ mobilization in cultured rat vascular smooth‐muscle cells | Zendy

T Akimoto | Zendy; E Kusano | Zendy; Naruhiro Fujita | Zendy; Koji Okada | Zendy; Osamu Saitô | Zendy; Shuichi Ono | Zendy; Yukio Ando | Zendy; Sumiko Homma | Zendy; Takako Saitô | Zendy; Yoshihiro Asano | Zendy

Open Access

Erythropoietin modulates angiotensin II‐ or noradrenaline‐induced Ca2+ mobilization in cultured rat vascular smooth‐muscle cells

Author(s) -

T Akimoto,

E Kusano,

Naruhiro Fujita,

Koji Okada,

Osamu Saitô,

Shuichi Ono,

Yukio Ando,

Sumiko Homma,

Takako Saitô,

Yoshihiro Asano

Publication year - 2001

Publication title -

nephrology dialysis transplantation

Language(s) - Uncategorized

Resource type - Journals

SCImago Journal Rank - 1.654

H-Index - 168

eISSN - 1460-2385

pISSN - 0931-0509

DOI - 10.1093/ndt/16.3.491

Subject(s) - endocrinology , medicine , extracellular , vascular smooth muscle , angiotensin ii , calphostin c , protein kinase c , calphostin , calcium , fura 2 , erythropoietin , cytosol , intracellular , biology , kinase , biochemistry , receptor , enzyme , smooth muscle

It has been reported that human recombinant erythropoietin (rHuEpo) modulates the sensitivity of the cardiovascular system to angiotensin II (Ang II) or noradrenaline (NA). In the present study, we explored the effect of rHuEpo on the responsiveness of Ang II- or NA-induced cytosolic free calcium ([Ca(2+)]i) mobilization in cultured rat vascular smooth-muscle cells (VSMC).

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