Combined liver–kidney transplantation for primary hyperoxaluria type 1 in young children | Zendy

Sally R. Ellis | Zendy; SallyAnne Hulton | Zendy; Patrick McKiernan | Zendy; Jean de Ville de Goyet | Zendy; Déirdre Kelly | Zendy

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Combined liver–kidney transplantation for primary hyperoxaluria type 1 in young children

Author(s) -

Sally R. Ellis,

SallyAnne Hulton,

Patrick McKiernan,

Jean de Ville de Goyet,

Déirdre Kelly

Publication year - 2001

Publication title -

nephrology dialysis transplantation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.654

H-Index - 168

eISSN - 1460-2385

pISSN - 0931-0509

DOI - 10.1093/ndt/16.2.348

Subject(s) - medicine , primary hyperoxaluria , transplantation , nephrocalcinosis , liver transplantation , dialysis , kidney , surgery , peritoneal dialysis , urinary system , hemodialysis , gastroenterology

Primary hyperoxaluria type 1 (PH1) is a rare condition in which deficiency of the liver enzyme alanine:glyoxylate aminotransferase leads to renal failure and systemic oxalosis. Combined liver-kidney transplantation (LKT) is recommended for end-stage renal failure (ESRF) in adults, but management of infants and young children is controversial. We retrospectively reviewed six children who underwent LKT for PH1.

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