Effects of continuous haemofiltration vs intermittent haemodialysis on systemic haemodynamics and splanchnic regional perfusion in septic shock patients: a prospective, randomized clinical trial | Zendy

Stefan John | Zendy; Daniela Griesbach | Zendy; Mathias Baumgärtel | Zendy; H. Weihprecht | Zendy; Roland E. Schmieder | Zendy; Helmut Geiger | Zendy

Open Access

Effects of continuous haemofiltration vs intermittent haemodialysis on systemic haemodynamics and splanchnic regional perfusion in septic shock patients: a prospective, randomized clinical trial

Author(s) -

Stefan John,

Daniela Griesbach,

Mathias Baumgärtel,

H. Weihprecht,

Roland E. Schmieder,

Helmut Geiger

Publication year - 2001

Publication title -

nephrology dialysis transplantation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.654

H-Index - 168

eISSN - 1460-2385

pISSN - 0931-0509

DOI - 10.1093/ndt/16.2.320

Subject(s) - medicine , splanchnic , septic shock , splanchnic circulation , shock (circulatory) , perfusion , hemodynamics , hemofiltration , prospective cohort study , randomized controlled trial , intensive care , intensive care medicine , anesthesia , hemodialysis , sepsis , surgery , cardiology

Parameters of splanchnic regional perfusion, like intramucosal pH (pHi) and pCO(2) (pCO(2)i), may predict outcome in septic shock patients. Continuous venovenous haemofiltration (CVVH) has been considered beneficial in haemodynamically unstable septic shock patients. In a prospective, randomized, clinical study, we investigated whether CVVH, in comparison to intermittent haemodialysis (IHD), is able to improve splanchnic regional perfusion in critically ill patients.

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