Open AccessThe anti‐proliferative effect of calcitriol on HL‐60 cells is neutralized by uraemic biological fluids
Author(s) -
Griet Glorieux,
Chen H. Hsu,
Rita De Smet,
Annemieke Dhondt,
John van Emmelo,
MarieAnne Waterloos,
Norbert Lameire,
Jean Plum,
Raymond Vanholder
Publication year - 2001
Publication title -
nephrology dialysis transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.654
H-Index - 168
eISSN - 1460-2385
pISSN - 0931-0509
DOI - 10.1093/ndt/16.2.246
Subject(s) - calcitriol , calcitriol receptor , endocrinology , medicine , in vitro , cell culture , cd14 , microbiology and biotechnology , receptor , biology , vitamin d and neurology , biochemistry , genetics
It has been demonstrated that uraemic serum/ultrafiltrate inhibits cell-mediated immune response in vitro, and that it suppresses calcitriol synthesis and its biological actions.
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