
Blood oxidative stress and lipoprotein oxidizability in haemodialysis patients: effect of the use of a vitamin E‐coated dialysis membrane
Author(s) -
Dominique Bonnefont–Rousselot,
Eric Lehmann,
MarieChantal Jaudon,
Jacques Delattre,
B Perrone,
JeanPierre Rechke
Publication year - 2000
Publication title -
nephrology dialysis transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.654
H-Index - 168
eISSN - 1460-2385
pISSN - 0931-0509
DOI - 10.1093/ndt/15.12.2020
Subject(s) - medicine , oxidative stress , hemodialysis , dialysis , vitamin e , lipoprotein , dialysis tubing , vitamin , membrane , biochemistry , cholesterol , antioxidant , chemistry
Oxidative stress has been shown in haemodialysis patients in relation with an increased production of free radicals due to membrane-induced complement and leukocyte activation. In order to minimize membrane bioincompatibility and thereby oxidative stress, more compatible filters have been perfected. Among them, a high-flux vitamin E-coated membrane (CL-EE) has been proposed recently. In vivo, little data is available on the consequences of the use of vitamin E-coated membranes. In the present study, the effects of a 3-month use of CL-EE dialysis membranes compared to conventional membranes have been evaluated in 12 haemodialysis patients on the blood oxidative stress status before and after the dialysis session.
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