Dialysis in neonates with inborn errors of metabolism | Zendy

Franz Schaefer | Zendy

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Dialysis in neonates with inborn errors of metabolism

Author(s) -

Franz Schaefer

Publication year - 1999

Publication title -

nephrology dialysis transplantation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.654

H-Index - 168

eISSN - 1460-2385

pISSN - 0931-0509

DOI - 10.1093/ndt/14.4.910

Subject(s) - maple syrup urine disease , medicine , dialysis , peritoneal dialysis , urea cycle , coma (optics) , inborn error of metabolism , anesthesia , arginine , leucine , biochemistry , chemistry , physics , amino acid , optics

Certain inborn errors of metabolism become manifest during the neonatal period by acute accumulation of neurotoxic metabolites leading to coma and death or irreversible neurological damage. Outcome critically depends on the immediate elimination of the accumulated neurotoxins. Recent technological progress provides improved tools to optimize the efficacy of neonatal dialysis.

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