Open AccessIL-10 synthesis and secretion by peripheral blood mononuclear cells in haemodialysis patients
Author(s) -
P Brunet
Publication year - 1998
Publication title -
nephrology dialysis transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.654
H-Index - 168
eISSN - 1460-2385
pISSN - 0931-0509
DOI - 10.1093/ndt/13.7.1745
Subject(s) - medicine , peripheral blood mononuclear cell , secretion , hemodialysis , endocrinology , gastroenterology , in vitro , biology , biochemistry
IL-10 may explain the paradox between immunodeficiency and oversecretion of cytokines in chronic haemodialysis (HD) patients. We analysed the secretion of IL-10 by PBMC and the expression of IL-10 mRNA in 10 long-term HD patients (108-276 months), 10 short-term HD patients (3-18 months), and 10 healthy controls.
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