Evidence for disturbed S-adenosylmethionine: S-adenosylhomocysteine ratio in patients with end-stage renal failure: a cause for disturbed methylation reactions? | Zendy

F. Loehrer | Zendy; Christof Angst | Zendy; Felix Brunner | Zendy; Walter E. Haefeli | Zendy; Brian Fowler | Zendy

Open Access

Evidence for disturbed S-adenosylmethionine: S-adenosylhomocysteine ratio in patients with end-stage renal failure: a cause for disturbed methylation reactions?

Author(s) -

F. Loehrer,

Christof Angst,

Felix Brunner,

Walter E. Haefeli,

Brian Fowler

Publication year - 1998

Publication title -

nephrology dialysis transplantation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.654

H-Index - 168

eISSN - 1460-2385

pISSN - 0931-0509

DOI - 10.1093/ndt/13.3.656

Subject(s) - homocysteine , medicine , endocrinology , metabolite , vitamin b12 , methylation , hyperhomocysteinemia , end stage renal disease , dialysis , hemodialysis , biochemistry , chemistry , gene

Elevated homocysteine concentrations have been associated with premature arteriosclerosis and with impairment of key methylation reactions through accumulation of the homocysteine metabolite S-adenosylhomocysteine. In end-stage renal failure high homocysteine concentrations are commonly found but thus far the concentrations of related adenosylated metabolites in plasma have not been assessed.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research