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Effects of a nitric oxide synthesis inhibitor on renal sodium handling and diluting capacity in humans
Author(s) -
Lioe-Ting Dijkhorst-Oei,
H. A. Koomans
Publication year - 1998
Publication title -
nephrology dialysis transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.654
H-Index - 168
eISSN - 1460-2385
pISSN - 0931-0509
DOI - 10.1093/ndt/13.3.587
Subject(s) - endocrinology , medicine , plasma renin activity , renal function , fractional excretion of sodium , sodium , natriuresis , urine sodium , urine flow rate , aldosterone , excretion , renal blood flow , nitric oxide , diuresis , chemistry , renin–angiotensin system , blood pressure , organic chemistry
Inhibition of nitric oxide (NO) synthesis has antinatriuretic and antidiuretic effects. Limited information is available on the role of NO in tubular sodium transport in the human kidney.

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