Haemolytic-uraemic syndrome and thrombotic-thrombocytopenic purpura in adults: clinical findings and prognostic factors for death and end-stage renal disease | Zendy

Markus Hollenbeck | Zendy; B. Kutkuhn | Zendy; C. Aul | Zendy; M. Leschke | Zendy; R. Willers | Zendy; B. Grabensee | Zendy

Open Access

Haemolytic-uraemic syndrome and thrombotic-thrombocytopenic purpura in adults: clinical findings and prognostic factors for death and end-stage renal disease

Author(s) -

Markus Hollenbeck,

B. Kutkuhn,

C. Aul,

M. Leschke,

R. Willers,

B. Grabensee

Publication year - 1998

Publication title -

nephrology dialysis transplantation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.654

H-Index - 168

eISSN - 1460-2385

pISSN - 0931-0509

DOI - 10.1093/ndt/13.1.76

Subject(s) - medicine , thrombotic thrombocytopenic purpura , end stage renal disease , gastroenterology , dialysis , creatinine , disease , hemodialysis , kidney disease , surgery , platelet

Left untreated, haemolytic-uraemic syndrome (HUS) and thrombotic-thrombocytopenic purpura (TTP) in adults have a poor prognosis with mortality rates reaching 90%. Patients who survive often develop end-stage renal disease. Because of similarities in clinical and morphological findings, both diseases are considered as one entity referred to as HUS-TTP syndrome.

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