The renoprotective effect of angiotensin-converting enzyme inhibitors in experimental chronic renal failure is not dependent on enhanced kinin activity | Zendy

Alexander Nabokov | Zendy; Kerstin Amann | Zendy; Peter Gaßmann | Zendy; Ulrich S. Schwarz | Zendy; Stephan R. Orth | Zendy; Eberhard Ritz | Zendy

Open Access

The renoprotective effect of angiotensin-converting enzyme inhibitors in experimental chronic renal failure is not dependent on enhanced kinin activity

Author(s) -

Alexander Nabokov,

Kerstin Amann,

Peter Gaßmann,

Ulrich S. Schwarz,

Stephan R. Orth,

Eberhard Ritz

Publication year - 1998

Publication title -

nephrology dialysis transplantation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.654

H-Index - 168

eISSN - 1460-2385

pISSN - 0931-0509

DOI - 10.1093/ndt/13.1.173

Subject(s) - medicine , bradykinin , glomerulosclerosis , kinin , angiotensin converting enzyme , chronic renal failure , renin–angiotensin system , endocrinology , enzyme inhibitor , angiotensin ii , pharmacology , enzyme , kidney , proteinuria , receptor , blood pressure , biochemistry , chemistry

Angiotensin-converting enzyme (ACE) inhibitors have been shown to ameliorate the progression of glomerulosclerosis both in experimental models of uraemia and in patients with renal failure. It has not been documented, however, whether this is due to a decrease in angiotensin II generation or is a consequence of elevated local level of bradykinin.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research