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Lipoprotein abnormalities are associated with increased rate of progression of human chronic renal insufficiency
Author(s) -
Ola Samuelsson,
H. Mulec,
Carolyn KnightGibson,
P.-O. Attman,
B Kron,
Robert Larsson,
Lars Weiss,
Hans Wedel,
Petar Alaupovic
Publication year - 1997
Publication title -
nephrology dialysis transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.654
H-Index - 168
eISSN - 1460-2385
pISSN - 0931-0509
DOI - 10.1093/ndt/12.9.1908
Subject(s) - medicine , renal function , kidney disease , endocrinology , lipoprotein , apolipoprotein b , proteinuria , nephrotic syndrome , population , cholesterol , kidney , gastroenterology , urology , environmental health
Chronic renal insufficiency is accompanied by specific alterations of the lipoprotein metabolism. It has been suggested that the renal dyslipoproteinaemia of renal insufficiency contributes to the progression of glomerular and tubular lesions, with subsequent deterioration of renal function. The objective of this prospective study was to investigate whether the specific lipoprotein abnormalities of renal insufficiency are associated with the rate of decline of renal function in patients with moderately advanced chronic renal failure.

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