Expression of cell adhesion molecules in primary renal disease and renal allograft rejection | Zendy

I. Häuser | Zendy; R. Riess | Zendy; Birgit Hausknecht | Zendy; H. Thuringer | Zendy; R. Bernd Sterzel | Zendy

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Expression of cell adhesion molecules in primary renal disease and renal allograft rejection

Author(s) -

I. Häuser,

R. Riess,

Birgit Hausknecht,

H. Thuringer,

R. Bernd Sterzel

Publication year - 1997

Publication title -

nephrology dialysis transplantation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.654

H-Index - 168

eISSN - 1460-2385

pISSN - 0931-0509

DOI - 10.1093/ndt/12.6.1122

Subject(s) - medicine , cell adhesion molecule , kidney disease , primary (astronomy) , disease , adhesion , transplantation , kidney , pathology , immunology , urology , chemistry , physics , organic chemistry , astronomy

In vitro studies have demonstrated that inflammatory mediators such as the cytokines TNF alpha and IL-1 upregulate or induce de novo expression of cell adhesion molecules on endothelial and epithelial cells. In the present study the expression of the cell adhesion molecules ICAM-1, VCAM-1, E-selectin and PECAM-1 was investigated in renal biopsies from patients with primary renal diseases (n = 66) and from renal allograft recipients (n = 42).

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