Apoptosis in proliferative glomerulonephritis: decreased apoptosis expression in lupus nephritis | Zendy

Haydee Soto | Zendy; Jesús Mosquera | Zendy; Bernardo RodríguezIturbe | Zendy; Ch. Roche | Zendy; Anna Maria Pinto | Zendy

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Apoptosis in proliferative glomerulonephritis: decreased apoptosis expression in lupus nephritis

Author(s) -

Haydee Soto,

Jesús Mosquera,

Bernardo RodríguezIturbe,

Ch. Roche,

Anna Maria Pinto

Publication year - 1997

Publication title -

nephrology dialysis transplantation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.654

H-Index - 168

eISSN - 1460-2385

pISSN - 0931-0509

DOI - 10.1093/ndt/12.2.273

Subject(s) - lupus nephritis , glomerulonephritis , medicine , apoptosis , nephritis , pathology , immunology , proliferating cell nuclear antigen , systemic lupus erythematosus , mesangial proliferative glomerulonephritis , kidney , immunohistochemistry , biology , disease , biochemistry

Apoptosis is a mechanism of cellular death involved in the deletion of cells in hyperplasic processes which has been observed in proliferative glomerulonephritis. Patients with systemic lupus erythematosus (SLE) are known to have defective apoptosis but there is scarce information about apoptosis in the renal lesions of this disease. The present studies were done to evaluate apoptosis in relation to the intensity of proliferation in several glomerulonephritis and the possible association between this relationship and the chronic histologic changes in lupus nephritis.

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