Open AccessDiabetic nephropathy: molecular analysis of extracellular matrix and clinical studies update
Author(s) -
William J. Pavan,
R. D. Eastman,
Liliane J. Striker
Publication year - 1996
Publication title -
nephrology dialysis transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.654
H-Index - 168
eISSN - 1460-2385
pISSN - 0931-0509
DOI - 10.1093/ndt/11.supp5.58
Subject(s) - diabetic nephropathy , medicine , endocrinology , glomerulosclerosis , streptozotocin , diabetes mellitus , nephropathy , renal function , kidney , proteinuria
Progressive glomerulosclerosis associated with decreasing kidney function, resulting in end-stage renal failure, is the major finding in diabetic nephropathy. There are multiple components of the extracellular matrix, and neither the exact composition nor the factors responsible for its increase in diabetic nephropathy is known.
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