Open AccessAcridone-labeled DNA aptamer for the detection of biomolecules
Author(s) -
Hiroaki Ozaki,
Yoshihiro Hagiwara,
Hirotaka Asakura,
Masayasu Kuwahara
Publication year - 2009
Publication title -
nucleic acids symposium series
Language(s) - English
Resource type - Journals
eISSN - 1746-8272
pISSN - 0261-3166
DOI - 10.1093/nass/nrp128
Subject(s) - acridone , aptamer , biomolecule , dna , chemistry , molecule , quenching (fluorescence) , biophysics , fluorescence , biochemistry , stereochemistry , microbiology and biotechnology , biology , organic chemistry , physics , quantum mechanics
An acridone-labeled DNA aptamer was synthesized to produce an aptamer probe. This aptamer probe could detect a specific molecule based on conformational changes upon binding of the specific molecules and the quenching of acridone emission.
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