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Monitoring biological interactions using perforated evanescent-field-coupled waveguide-mode nanobiosensors
Author(s) -
Subash C. B. Gopinath,
K. Awazu,
Makoto Fujimaki,
Junji Tominaga,
K.C. Gupta,
Penmetcha K. R. Kumar
Publication year - 2009
Publication title -
nucleic acids symposium series
Language(s) - Uncategorized
Resource type - Journals
eISSN - 1746-8272
pISSN - 0261-3166
DOI - 10.1093/nass/nrp047
Subject(s) - evanescent wave , waveguide , nucleic acid , field (mathematics) , biomolecule , optics , materials science , optoelectronics , nanotechnology , physics , chemistry , mathematics , biochemistry , pure mathematics
Evanescent-field-coupled (EFC) waveguide-mode sensors recently been shown to be suitable for detecting various biomolecules. In the present studies, we demonstrated that both nucleic acids hybridization and nucleic acids-protein interactions can be analyzed using perforated evanescent-field-coupled waveguide-mode nanobio-sensors.

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