Open AccessSynthesis and antiviral evaluation of 4-fluoropyrazole-3-carboxamide nucleoside derivatives
Author(s) -
Frédéric Leroy,
Dominique Chaves,
David Dukhan,
Richard Storer,
J P Sommadossi,
A. G. Loi,
Alessandra Cadeddu,
Maura Fanti,
N. Boscu,
F. Bassetti,
Michel Liuzzi,
G. Gosselin
Publication year - 2008
Publication title -
nucleic acids symposium series
Language(s) - English
Resource type - Journals
eISSN - 1746-8272
pISSN - 0261-3166
DOI - 10.1093/nass/nrn312
Subject(s) - carboxamide , nucleoside , chemistry , combinatorial chemistry , virology , stereochemistry , biology
A series of novel 4-fluoro-1H-pyrazole-3-carboxamide nucleoside analogues were synthesized and evaluated as potential inhibitors of RNA virus replication, including hepatitis C virus (HCV).
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