Open AccessThe Novel unsaturated acyclic nucleoside analogues: cytostatic and antiviral activity evaluations
Author(s) -
Karlo Wittine,
K. Benci,
Sandra Kraljević Pavelić,
Krešimir Pavelić,
Mladen Mintas
Publication year - 2008
Publication title -
nucleic acids symposium series
Language(s) - English
Resource type - Journals
eISSN - 1746-8272
pISSN - 0261-3166
DOI - 10.1093/nass/nrn304
Subject(s) - pyrimidine , potency , purine , stereochemistry , chemistry , nucleoside , nucleoside analogue , combinatorial chemistry , biochemistry , in vitro , enzyme
The novel pyrimidine (3-6) and purine (12-19) acyclic nucleoside analogues containing (Z) 4-amino or 4-aminohydrochloride-2-butenyl side chain (Fig.) were synthesized to evaluate their antiviral and cytostatic activity potency.
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