Radiolytic Ligation of Oligodeoxynucleotides Possessing Disulfide Bond | Zendy

Kazuhito Tanabe | Zendy; E. Kuraseko | Zendy; E. Matsumoto | Zendy; H. Yamada | Zendy; Takeo Itô | Zendy; Satoshi Nishimoto | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Radiolytic Ligation of Oligodeoxynucleotides Possessing Disulfide Bond

Author(s) -

Kazuhito Tanabe,

E. Kuraseko,

E. Matsumoto,

H. Yamada,

Takeo Itô,

Satoshi Nishimoto

Publication year - 2008

Publication title -

nucleic acids symposium series

Language(s) - Uncategorized

Resource type - Journals

eISSN - 1746-8272

pISSN - 0261-3166

DOI - 10.1093/nass/nrn233

Subject(s) - radiolysis , ligation , disulfide bond , chemistry , aqueous solution , irradiation , solvated electron , redox , photochemistry , biophysics , combinatorial chemistry , biochemistry , inorganic chemistry , organic chemistry , microbiology and biotechnology , biology , physics , nuclear physics

Hypoxic X-radiolysis of diluted aqueous solutions was performed to generate hydrated electrons that induced one-electron reduction of oligodeoxynucleotides (ODNs) possessing a disulfide bond. Upon hypoxic irradiation, reductive ligation reaction between two types of ODNs occurred in the presence of a template ODN strand, resulting in the formation of a prescribed ODN in substantial amounts.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research