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Isoenergetic microarray mapping is shown to be an ideal method for probing subtle structural differences between initiator tRNA(i)(Met) and elongator tRNA(m)(Met) from Lupinus luteus. The differences in structure of both tRNAs cause significant dissimilarities in binding to microarrays probes.

Isoenergetic microarray mapping reveals differences in structure between tRNAiMet and tRNAmMet from Lupinus luteus