RNA analysis with a novel fluorescent oligonucleotide | Zendy

Takeshi Kubota | Zendy; Shuji Ikeda | Zendy; Akimitsu Okamoto | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

RNA analysis with a novel fluorescent oligonucleotide

Author(s) -

Takeshi Kubota,

Shuji Ikeda,

Akimitsu Okamoto

Publication year - 2007

Publication title -

nucleic acids symposium series

Language(s) - English

Resource type - Journals

eISSN - 1746-8272

pISSN - 0261-3166

DOI - 10.1093/nass/nrm146

Subject(s) - oligonucleotide , fluorescence , fluorophore , rna , dna , oligomer restriction , computational biology , biophysics , biology , chemistry , microbiology and biotechnology , biochemistry , gene , physics , quantum mechanics

We have designed and synthesized a novel fluorescent oligonucleotide to analyze functions of RNAs. This probe worked as a green fluorophore only when making a stable double-strand with DNA or RNA. The fluorescence enhancement is rapid, large and target specific. Therefore, this probe has an ideal photophysical property as a fluorescent probe. We applied a fluorescent oligonucleotide to living cells to confirm the condition for introducing the probe. This novel probe and analyzing method will be a very useful tool for understanding RNA functions.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research