Open AccessPhotochemical Synthesis of R-shaped DNA via 5-Cyanovinyldeoxyuridine
Author(s) -
Masayuki Ogino,
Kenzo Fujimoto
Publication year - 2007
Publication title -
nucleic acids symposium series
Language(s) - Uncategorized
Resource type - Journals
eISSN - 1746-8272
pISSN - 0261-3166
DOI - 10.1093/nass/nrm116
Subject(s) - photochemistry , chemistry , computational biology , biology
We now report template-directed photoligation using ODN containing alpha(C)U and beta(C)U at both terminal ends. By using this method, we performed template-directed photoligation in two positions at the middle of DNA and synthesized R-shaped DNA as novel structure. The isolated R-shaped DNA was characterized by MALDI-TOF MS and enzymatic digestion.
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