Open AccessSynthesis of DNA duplexes containing complexes of 5-modified pyrimidine bases and metal ions
Author(s) -
Kazunari Iwamoto,
K. Hayashi,
Yusuke Watanabe,
Isaku Okamoto,
Akira Ono
Publication year - 2007
Publication title -
nucleic acids symposium series
Language(s) - English
Resource type - Journals
eISSN - 1746-8272
pISSN - 0261-3166
DOI - 10.1093/nass/nrm091
Subject(s) - uracil , pyrimidine , chemistry , metal ions in aqueous solution , metal , dna , residue (chemistry) , ion , combinatorial chemistry , stereochemistry , organic chemistry , biochemistry
DNA duplexes carrying metal ions at the 5-position of uracil residues were synthesized by mixing oligodeoxyribonucleotides (ODNs) containing 5-formyl uracils, metal ions, and amines. A metal ion binding site may form from the 5-formyl residue and amines.
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