Open AccessAlignment of pyrene aromatics along RNA double helix
Author(s) -
Yukinori Ohtoshi,
Mitsunobu Nakamura,
Kazushige Yamana
Publication year - 2005
Publication title -
nucleic acids symposium series
Language(s) - English
Resource type - Journals
eISSN - 1746-8272
pISSN - 0261-3166
DOI - 10.1093/nass/49.1.141
Subject(s) - pyrene , excimer , stacking , duplex (building) , rna , fluorescence , chemistry , helix (gastropod) , photochemistry , biophysics , crystallography , organic chemistry , biochemistry , physics , biology , dna , optics , ecology , snail , gene
Multiple pyrene modified RNA duplex exhibits pyrene excimer fluorescence. The pyrene excimer fluorescence is significantly enhanced with an increase in the number of incorporated pyrenes. The pyrenes in the RNA helically aggregate with partial pi-stacking along outside of double stranded helical backbone.
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