Open AccessThe structure and function of tRNA-like domain in E. coli tmRNA
Author(s) -
Kazuo Hanawa,
Stephen Lee,
Hyouta Himeno,
Akira Muto
Publication year - 2000
Publication title -
nucleic acids symposium series
Language(s) - English
Resource type - Journals
eISSN - 1746-8272
pISSN - 0261-3166
DOI - 10.1093/nass/44.1.263
Subject(s) - transfer rna , translation (biology) , messenger rna , function (biology) , rna , biology , genetics , computational biology , microbiology and biotechnology , gene
mRNA has a dual function both as a tRNA and as an mRNA in trans-translation. tmRNA possesses structural elements similar to canonical tRNAs. Our mutation studies show that the tRNA-like structure is crucial for function as an mRNA as well as a tRNA.
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