Metal ion-directed outside binding of small DNA ligand | Zendy

Toshihiro Ihara | Zendy; Takashi Ikegami | Zendy; T. Fujii | Zendy; Yusuke Kitamura | Zendy; Shinji Sueda | Zendy; Makoto Takagi | Zendy; Nicholas E. Geacintov | Zendy; Akinori Jyo | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Metal ion-directed outside binding of small DNA ligand

Author(s) -

Toshihiro Ihara,

Takashi Ikegami,

T. Fujii,

Yusuke Kitamura,

Shinji Sueda,

Makoto Takagi,

Nicholas E. Geacintov,

Akinori Jyo

Publication year - 2003

Publication title -

nucleic acids symposium series

Language(s) - English

Resource type - Journals

eISSN - 1746-8272

pISSN - 0261-3166

DOI - 10.1093/nass/3.1.85

Subject(s) - dna , dimer , chemistry , pyridinium , ligand (biochemistry) , crystallography , duplex (building) , metal , stereochemistry , biochemistry , receptor , medicinal chemistry , organic chemistry

DNA binding of the ligand bearing an oxine and a pyridinium group was regulated by coexisting Cu2+ over the binding constant range of three orders of magnitude. The ligands coordinated to Cu2+ to form a dimer and then cooperatively bound outside of DNA duplex to give the well-regulated 1-D structure along the DNA backbone.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research