Helix formation of oligodeoxyribonucleotides containing base-aromatic ring conjugates | Zendy

Mio Kubota | Zendy; Momo Kosuge | Zendy; Akira Ono | Zendy

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Helix formation of oligodeoxyribonucleotides containing base-aromatic ring conjugates

Author(s) -

Mio Kubota,

Momo Kosuge,

Akira Ono

Publication year - 2003

Publication title -

nucleic acids symposium series

Language(s) - English

Resource type - Journals

eISSN - 1746-8272

pISSN - 0261-3166

DOI - 10.1093/nass/3.1.77

Subject(s) - pyrene , conjugate , chemistry , nucleoside , duplex (building) , stereochemistry , ring (chemistry) , helix (gastropod) , fluorescence , tandem , dna , combinatorial chemistry , biochemistry , organic chemistry , biology , mathematical analysis , ecology , physics , mathematics , quantum mechanics , snail , materials science , composite material

Novel nucleoside analogues with base moieties containing pyrene groups have been synthesized and incorporated into oligodeoxyribonucleotides (ODNs). ODNs containing tandem pyrene residues at the 5'-end gave fluorescence spectra characteristic of eximers that were diminished by duplex formation of the ODNs with complementary strands.

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