Open AccessPhotoreactivity of 5-iodouracil-containing telomeric DNA
Author(s) -
Yan Xu,
H. Sugiyama
Publication year - 2003
Publication title -
nucleic acids symposium series
Language(s) - English
Resource type - Journals
eISSN - 1746-8272
pISSN - 0261-3166
DOI - 10.1093/nass/3.1.71
Subject(s) - antiparallel (mathematics) , oligonucleotide , dna , ion , chemistry , crystallography , g quadruplex , stereochemistry , biophysics , biochemistry , biology , physics , organic chemistry , quantum mechanics , magnetic field
The photoreaction of 5-iodouracil-((I)U)-containing telomeric oligonucleotides in parallel or antiparallel structures, generated in the presence of K+ or Na+ ions, was investigated. It was found that the photoreactivity of telomeric DNA depends on the differences in the quadruplex conformations in the presence of K+ or Na+ ions.
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