Analysis of processing-defective variants of human tRNA(Val) | Zendy

Yoshio Kato | Zendy; Masayuki Sano | Zendy; Kazunari Taira | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Analysis of processing-defective variants of human tRNA(Val)

Author(s) -

Yoshio Kato,

Masayuki Sano,

Kazunari Taira

Publication year - 2003

Publication title -

nucleic acids symposium series

Language(s) - English

Resource type - Journals

eISSN - 1746-8272

pISSN - 0261-3166

DOI - 10.1093/nass/3.1.283

Subject(s) - cytoplasm , nucleus , transfer rna , gene , hela , in situ hybridization , protein biosynthesis , biology , microbiology and biotechnology , messenger rna , genetics , rna , cell culture

Eukaryotic tRNAs are transcribed, processed and exported from the nucleus to the cytoplasm to participate in protein biosynthesis. A variant of human gene for tRNA(Val), HtV4, is not processed neither its 5'- nor its 3'-flanking sequences. By RT-PCR analysis and in situ hybridization, we demonstrated that the HtV4 was constitutively expressed without processing, and localized in the nucleus in HeLa cells.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research