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Transcriptome visualization and data availability at the Saccharomyces Genome Database
Author(s) -
Patrick Ng,
Edith D. Wong,
Kevin MacPherson,
Suzi Aleksander,
Joanna Argasinska,
Barbara Dunn,
Robert S Nash,
Marek S. Skrzypek,
Felix Gondwe,
Sagar Jha,
Kalpana Karra,
Shuai Weng,
Stuart R. Miyasato,
Matt Simison,
Stacia R. Engel,
J. Michael Cherry
Publication year - 2019
Publication title -
nucleic acids research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 9.008
H-Index - 537
eISSN - 1362-4954
pISSN - 0305-1048
DOI - 10.1093/nar/gkz892
Subject(s) - biology , genome , saccharomyces cerevisiae , annotation , computational biology , transcriptome , genome browser , visualization , genetics , gene , genome project , database , genomics , gene expression , data mining , computer science
The Saccharomyces Genome Database (SGD; www.yeastgenome.org) maintains the official annotation of all genes in the Saccharomyces cerevisiae reference genome and aims to elucidate the function of these genes and their products by integrating manually curated experimental data. Technological advances have allowed researchers to profile RNA expression and identify transcripts at high resolution. These data can be configured in web-based genome browser applications for display to the general public. Accordingly, SGD has incorporated published transcript isoform data in our instance of JBrowse, a genome visualization platform. This resource will help clarify S. cerevisiae biological processes by furthering studies of transcriptional regulation, untranslated regions, genome engineering, and expression quantification in S. cerevisiae.

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