The SCOP database in 2020: expanded classification of representative family and superfamily domains of known protein structures | Zendy

Antonina Andreeva | Zendy; Eugene Kulesha | Zendy; Julian Gough | Zendy; Alexey G. Murzin | Zendy

Open Access

The SCOP database in 2020: expanded classification of representative family and superfamily domains of known protein structures

Author(s) -

Antonina Andreeva,

Eugene Kulesha,

Julian Gough,

Alexey G. Murzin

Publication year - 2019

Publication title -

nucleic acids research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 9.008

H-Index - 537

eISSN - 1362-4954

pISSN - 0305-1048

DOI - 10.1093/nar/gkz1064

Subject(s) - structural classification of proteins database , biology , protein data bank (rcsb pdb) , schema (genetic algorithms) , database , protein data bank , protein domain , database schema , protein family , computational biology , bioinformatics , information retrieval , protein structure , computer science , genetics , database design , gene , biochemistry

The Structural Classification of Proteins (SCOP) database is a classification of protein domains organised according to their evolutionary and structural relationships. We report a major effort to increase the coverage of structural data, aiming to provide classification of almost all domain superfamilies with representatives in the PDB. We have also improved the database schema, provided a new API and modernised the web interface. This is by far the most significant update in coverage since SCOP 1.75 and builds on the advances in schema from the SCOP 2 prototype. The database is accessible from http://scop.mrc-lmb.cam.ac.uk.

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