DrugCentral 2018: an update | Zendy

Oleg Ursu | Zendy; Jayme Holmes | Zendy; Cristian Bologa | Zendy; Jeremy J. Yang | Zendy; Stephen L. Mathias | Zendy; Vasileios Stathias | Zendy; Ðắc-Trung Nguyễn | Zendy; Stephan C. Schürer | Zendy; Tudor I. Oprea | Zendy

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DrugCentral 2018: an update

Author(s) -

Oleg Ursu,

Jayme Holmes,

Cristian Bologa,

Jeremy J. Yang,

Stephen L. Mathias,

Vasileios Stathias,

Ðắc-Trung Nguyễn,

Stephan C. Schürer,

Tudor I. Oprea

Publication year - 2018

Publication title -

nucleic acids research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 9.008

H-Index - 537

eISSN - 1362-4954

pISSN - 0305-1048

DOI - 10.1093/nar/gky963

Subject(s) - adverse event reporting system , food and drug administration , biology , information retrieval , download , database , bioinformatics , computer science , world wide web , pharmacology

DrugCentral is a drug information resource (http://drugcentral.org) open to the public since 2016 and previously described in the 2017 Nucleic Acids Research Database issue. Since the 2016 release, 103 new approved drugs were updated. The following new data sources have been included: Food and Drug Administration (FDA) Adverse Event Reporting System (FAERS), FDA Orange Book information, L1000 gene perturbation profile distance/similarity matrices and estimated protonation constants. New and existing entries have been updated with the latest information from scientific literature, drug labels and external databases. The web interface has been updated to display and query new data. The full database dump and data files are available for download from the DrugCentral website.

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