The antiSMASH database version 2: a comprehensive resource on secondary metabolite biosynthetic gene clusters | Zendy

Kai Blin | Zendy; Victòria Andreu | Zendy; Emmanuel L. C. de los Santos | Zendy; Francesco Del Carratore | Zendy; Sang Yup Lee | Zendy; Marnix H. Medema | Zendy; Tilmann Weber | Zendy

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The antiSMASH database version 2: a comprehensive resource on secondary metabolite biosynthetic gene clusters

Author(s) -

Kai Blin,

Victòria Andreu,

Emmanuel L. C. de los Santos,

Francesco Del Carratore,

Sang Yup Lee,

Marnix H. Medema,

Tilmann Weber

Publication year - 2018

Publication title -

nucleic acids research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 9.008

H-Index - 537

eISSN - 1362-4954

pISSN - 0305-1048

DOI - 10.1093/nar/gky1060

Subject(s) - genome , biology , bacterial genome size , database , gene , computational biology , secondary metabolite , genetics , computer science

Natural products originating from microorganisms are frequently used in antimicrobial and anticancer drugs, pesticides, herbicides or fungicides. In the last years, the increasing availability of microbial genome data has made it possible to access the wealth of biosynthetic clusters responsible for the production of these compounds by genome mining. antiSMASH is one of the most popular tools in this field. The antiSMASH database provides pre-computed antiSMASH results for many publicly available microbial genomes and allows for advanced cross-genome searches. The current version 2 of the antiSMASH database contains annotations for 6200 full bacterial genomes and 18,576 bacterial draft genomes and is available at https://antismash-db.secondarymetabolites.org/.

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