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iDog: an integrated resource for domestic dogs and wild canids
Author(s) -
Bixia Tang,
Qing Zhou,
Lili Dong,
Wulue Li,
Xiangquan Zhang,
Li Lan,
Shuang Zhai,
Jingfa Xiao,
Zhang Zhang,
Yīmíng Bào,
YaPing Zhang,
Guodong Wang,
Wenming Zhao
Publication year - 2018
Publication title -
nucleic acids research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 9.008
H-Index - 537
eISSN - 1362-4954
pISSN - 0305-1048
DOI - 10.1093/nar/gky1041
Subject(s) - biology , annotation , genome , canis , computational biology , gene annotation , gene , genetics , ecology
The domestic dog (Canis lupus familiaris) is indisputably one of man's best friends. It is also a fundamental model for many heritable human diseases. Here, we present iDog (http://bigd.big.ac.cn/idog), the first integrated resource dedicated to domestic dogs and wild canids. It incorporates a variety of omics data, including genome sequences assemblies for dhole and wolf, genomic variations extracted from hundreds of dog/wolf whole genomes, phenotype/disease traits curated from dog research communities and public resources, gene expression profiles derived from published RNA-Seq data, gene ontology for functional annotation, homolog gene information for multiple organisms and disease-related literature. Additionally, iDog integrates sequence alignment tools for data analyses and a genome browser for data visualization. iDog will not only benefit the global dog research community, but also provide access to a user-friendly consolidation of dog information to a large number of dog enthusiasts.

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