The iceLogo web server and SOAP service for determining protein consensus sequences | Zendy

Davy Maddelein | Zendy; Niklaas Colaert | Zendy; Iain Buchanan | Zendy; Niels Hulstaert | Zendy; Kris Gevaert | Zendy; Lennart Martens | Zendy

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The iceLogo web server and SOAP service for determining protein consensus sequences

Author(s) -

Davy Maddelein,

Niklaas Colaert,

Iain Buchanan,

Niels Hulstaert,

Kris Gevaert,

Lennart Martens

Publication year - 2015

Publication title -

nucleic acids research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 9.008

H-Index - 537

eISSN - 1362-4954

pISSN - 0305-1048

DOI - 10.1093/nar/gkv385

Subject(s) - soap , biology , login , web server , web service , sequence (biology) , consensus sequence , service (business) , set (abstract data type) , computational biology , the internet , protocol (science) , web application , bioinformatics , computer science , world wide web , peptide sequence , programming language , genetics , computer network , gene , medicine , alternative medicine , economy , pathology , economics

The iceLogo web server and SOAP service implement the previously published iceLogo algorithm. iceLogo builds on probability theory to visualize protein consensus sequences in a format resembling sequence logos. Peptide sequences are compared against a reference sequence set that can be tailored to the studied system and the used protocol. As such, not only over- but also underrepresented residues can be visualized in a statistically sound manner, which further allows the user to easily analyse and interpret conserved sequence patterns in proteins. The web application and SOAP service can be found free and open to all users without the need for a login on http://iomics.ugent.be/icelogoserver/main.html.

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