Sensitive, multiplex and direct quantification of RNA sequences using a modified RASL assay | Zendy

H. Benjamin Larman | Zendy; Erick R. Scott | Zendy; Megan Wogan | Zendy; Glenn Oliveira | Zendy; Ali Torkamani | Zendy; Peter G. Schultz | Zendy

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Sensitive, multiplex and direct quantification of RNA sequences using a modified RASL assay

Author(s) -

H. Benjamin Larman,

Erick R. Scott,

Megan Wogan,

Glenn Oliveira,

Ali Torkamani,

Peter G. Schultz

Publication year - 2014

Publication title -

nucleic acids research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 9.008

H-Index - 537

eISSN - 1362-4954

pISSN - 0305-1048

DOI - 10.1093/nar/gku636

Subject(s) - biology , multiplex , oligonucleotide , computational biology , rna , dna , multiplex ligation dependent probe amplification , dna ligase , microbiology and biotechnology , genetics , gene , exon

A sensitive and highly multiplex method to directly measure RNA sequence abundance without requiring reverse transcription would be of value for a number of biomedical applications, including high throughput small molecule screening, pathogen transcript detection and quantification of short/degraded RNAs.

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