HoPaCI-DB: host-PseudomonasandCoxiellainteraction database | Zendy

Sophie Bleves | Zendy; Irmtraud Dunger | Zendy; Mathias C. Walter | Zendy; Dimitrios Frangoulidis | Zendy; Gabi Kastenmüller | Zendy; Romé Voulhoux | Zendy; Andreas Ruepp | Zendy

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HoPaCI-DB: host-PseudomonasandCoxiellainteraction database

Author(s) -

Sophie Bleves,

Irmtraud Dunger,

Mathias C. Walter,

Dimitrios Frangoulidis,

Gabi Kastenmüller,

Romé Voulhoux,

Andreas Ruepp

Publication year - 2013

Publication title -

nucleic acids research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 9.008

H-Index - 537

eISSN - 1362-4954

pISSN - 0305-1048

DOI - 10.1093/nar/gkt925

Subject(s) - biology , host (biology) , database , annotation , computational biology , virulence , coxiella burnetii , pseudomonas aeruginosa , bacteria , microbiology and biotechnology , bioinformatics , computer science , genetics , gene

Bacterial infectious diseases are the result of multifactorial processes affected by the interplay between virulence factors and host targets. The host-Pseudomonas and Coxiella interaction database (HoPaCI-DB) is a publicly available manually curated integrative database (http://mips.helmholtz-muenchen.de/HoPaCI/) of host-pathogen interaction data from Pseudomonas aeruginosa and Coxiella burnetii. The resource provides structured information on 3585 experimentally validated interactions between molecules, bioprocesses and cellular structures extracted from the scientific literature. Systematic annotation and interactive graphical representation of disease networks make HoPaCI-DB a versatile knowledge base for biologists and network biology approaches.

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