DigSee: disease gene search engine with evidence sentences (version cancer) | Zendy

Jeong-Kyun Kim | Zendy; Seongeun So | Zendy; Heejin Lee | Zendy; Jong Cheol Park | Zendy; JungJae Kim | Zendy; Hyunju Lee | Zendy

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DigSee: disease gene search engine with evidence sentences (version cancer)

Author(s) -

Jeong-Kyun Kim,

Seongeun So,

Heejin Lee,

Jong Cheol Park,

JungJae Kim,

Hyunju Lee

Publication year - 2013

Publication title -

nucleic acids research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 9.008

H-Index - 537

eISSN - 1362-4954

pISSN - 0305-1048

DOI - 10.1093/nar/gkt531

Subject(s) - biology , gene , computational biology , identification (biology) , disease , medline , biological pathway , genetics , bioinformatics , gene expression , ecology , medicine , biochemistry , pathology

Biological events such as gene expression, regulation, phosphorylation, localization and protein catabolism play important roles in the development of diseases. Understanding the association between diseases and genes can be enhanced with the identification of involved biological events in this association. Although biological knowledge has been accumulated in several databases and can be accessed through the Web, there is no specialized Web tool yet allowing for a query into the relationship among diseases, genes and biological events. For this task, we developed DigSee to search MEDLINE abstracts for evidence sentences describing that 'genes' are involved in the development of 'cancer' through 'biological events'. DigSee is available through http://gcancer.org/digsee.

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