ProKware: integrated software for presenting protein structural properties in protein tertiary structures | Zendy

JuiHung Hung | Zendy; Haidong Huang | Zendy; T.-Y. Lee | Zendy

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ProKware: integrated software for presenting protein structural properties in protein tertiary structures

Author(s) -

JuiHung Hung,

Haidong Huang,

T.-Y. Lee

Publication year - 2006

Publication title -

nucleic acids research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 9.008

H-Index - 537

eISSN - 1362-4954

pISSN - 0305-1048

DOI - 10.1093/nar/gkl235

Subject(s) - biology , protein tertiary structure , protein domain , protein structure , software , computational biology , domain (mathematical analysis) , interface (matter) , the internet , posttranslational modification , structural alignment , structural biology , bioinformatics , sequence alignment , computer science , peptide sequence , biochemistry , world wide web , programming language , enzyme , gene , mathematical analysis , pulmonary surfactant , gibbs isotherm , mathematics

Protein tertiary structure plays an essential role in deciphering protein functions, especially protein structural properties, including domains, active sites and post-translational modifications. These properties typically yield useful clues for understanding protein functions. This work presents an integrated software, named ProKware, that presents protein structural properties in protein tertiary structures, such as domains, functional sites, families, active sites, binding sites, post-translational modifications and domain-domain interaction. Using this web-based and Windows-based interface, users can manipulate and visualize three-dimensional protein structures, as well as the supported structural properties that are curated in the protein knowledge database. ProKware is an effective and convenient solution for investigating protein functions and structural relationships. This software can be accessed on the internet at http://ProKware.mbc.nctu.edu.tw/.

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