metaSHARK: a WWW platform for interactive exploration of metabolic networks
Author(s) -
Christopher J. T. Hyland,
John W. Pinney,
Glenn A. McConkey,
David R. Westhead
Publication year - 2006
Publication title -
nucleic acids research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 9.008
H-Index - 537
eISSN - 1362-4954
pISSN - 0305-1048
DOI - 10.1093/nar/gkl196
Subject(s) - upload , biology , kegg , metabolic network , context (archaeology) , visualization , the internet , web browser , genome browser , computational biology , genome , world wide web , web server , gene , bioinformatics , computer science , genomics , gene expression , transcriptome , genetics , data mining , paleontology
The metaSHARK (metabolic search and reconstruction kit) web server offers users an intuitive, fully interactive way to explore the KEGG metabolic network via a WWW browser. Metabolic reconstruction information for specific organisms, produced by our automated SHARKhunt tool or from other programs or genome annotations, may be uploaded to the website and overlaid on the generic network. Additional data from gene expression experiments can also be incorporated, allowing the visualization of differential gene expression in the context of the predicted metabolic network. metaSHARK is available at http://bioinformatics.leeds.ac.uk/shark/.
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