BLAST: improvements for better sequence analysis
Author(s) -
J. Ye,
Scott McGinnis,
Thomas Madden
Publication year - 2006
Publication title -
nucleic acids research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 9.008
H-Index - 537
eISSN - 1362-4954
pISSN - 0305-1048
DOI - 10.1093/nar/gkl164
Subject(s) - biology , sequence (biology) , sequence database , similarity (geometry) , sequence alignment , computational biology , sequence analysis , bioinformatics , information retrieval , genetics , computer science , peptide sequence , artificial intelligence , gene , image (mathematics)
Basic local alignment search tool (BLAST) is a sequence similarity search program. The National Center for Biotechnology Information (NCBI) maintains a BLAST server with a home page at http://www.ncbi.nlm.nih.gov/BLAST/. We report here on recent enhancements to the results produced by the BLAST server at the NCBI. These include features to highlight mismatches between similar sequences, show where the query was masked for low-complexity sequence, and integrate information about the database sequences from the NCBI Entrez system into the BLAST display. Changes to how the database sequences are fetched have also improved the speed of the report generator.
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