Open AccessPANDIT: an evolution-centric database of protein and associated nucleotide domains with inferred trees
Author(s) -
Simon Whelan
Publication year - 2005
Publication title -
nucleic acids research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 9.008
H-Index - 537
eISSN - 1362-4954
pISSN - 0305-1048
DOI - 10.1093/nar/gkj087
Subject(s) - phylogenetic tree , biology , multiple sequence alignment , phylogenetics , sequence alignment , protein sequencing , computational biology , protein family , tree (set theory) , evolutionary biology , genetics , database , peptide sequence , gene , computer science , mathematical analysis , mathematics
PANDIT is a database of homologous sequence alignments accompanied by estimates of their corresponding phylogenetic trees. It provides a valuable resource to those studying phylogenetic methodology and the evolution of coding-DNA and protein sequences. Currently in version 17.0, PANDIT comprises 7738 families of homologous protein domains; for each family, DNA and corresponding amino acid sequence multiple alignments are available together with high quality phylogenetic tree estimates. Recent improvements include expanded methods for phylogenetic tree inference, assessment of alignment quality and a redesigned web interface, available at the URL http://www.ebi.ac.uk/goldman-srv/pandit.
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