ADDA: a domain database with global coverage of the protein universe | Zendy

Andreas Heger | Zendy; Christopher Wilton | Zendy; Ashwin Sivakumar | Zendy; Liisa Holm | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

ADDA: a domain database with global coverage of the protein universe

Author(s) -

Andreas Heger,

Christopher Wilton,

Ashwin Sivakumar,

Liisa Holm

Publication year - 2004

Publication title -

nucleic acids research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 9.008

H-Index - 537

eISSN - 1362-4954

pISSN - 0305-1048

DOI - 10.1093/nar/gki096

Subject(s) - biology , domain (mathematical analysis) , database , protein domain , upload , computational biology , interface (matter) , protein–protein interaction , bioinformatics , computer science , genetics , world wide web , mathematical analysis , mathematics , gene , pulmonary surfactant , biochemistry , gibbs isotherm

We used the Automatic Domain Decomposition Algorithm (ADDA) to generate a database of protein domain families with complete coverage of all protein sequences. Sequences are split into domains and domains are grouped into protein domain families in a completely automated process. The current database contains domains for more than 1.5 million sequences in more than 40,000 domain families. In particular, there are 3828 novel domain families that do not overlap with the curated domain databases Pfam, SCOP and InterPro. The data are freely available for downloading and querying via a web interface (http://ekhidna.biocenter.helsinki.fi:9801/sqgraph/pairsdb).

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research