5'SAGE: 5'-end Serial Analysis of Gene Expression database
Author(s) -
Yusuke Kasai
Publication year - 2004
Publication title -
nucleic acids research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 9.008
H-Index - 537
eISSN - 1362-4954
pISSN - 0305-1048
DOI - 10.1093/nar/gki085
Subject(s) - serial analysis of gene expression , biology , sage , gene , genetics , database , transcription (linguistics) , intron , intergenic region , gene expression , promoter , computational biology , gene expression profiling , genome , computer science , linguistics , physics , philosophy , nuclear physics
To comprehensively identify transcription start sites and the frequencies of individual mRNAs in human cell libraries, a method of 5' end Serial Analysis of Gene Expression (SAGE) was developed recently, which makes it possible to collect a large amount of start site information, and subsequently, we have established a related database server called 5'SAGE. This database displays the observed frequencies of individual 5' end SAGE tags and previously unknown transcription start sites in the promoter regions, introns and intergenic regions of known genes. 5'SAGE will be useful for analyzing promoter regions and start site variation in different tissues, and is freely available at http://5sage.gi.k.u-tokyo.ac.jp/.
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